Poliomyelitis surveillance and vaccine efficacy in Bombay, 1982-87

ABSTRACT

Reported are updated data on poliomyelitis surveillance in Bombay for the period 1982-87 and estimates of the efficacy of oral poliovaccine (OPV) calculated by the case exposure method, using two approaches. The first, a screening technique that used only data on the reported number of doses of vaccine administered and the immunization status of all poliomyelitis cases, appeared to underestimate the true vaccine efficacy. In the more rigorous second technique, which used data for children of the same age group, geographical areas, and study year, obtained from immunization coverage surveys, and information on the immunization status of poliomyelitis cases, the results indicate that the OPV vaccine efficacy for fully immunized children aged 12-23 months exceeded 90 percent