Infecciones genitales por papilomavirus humanos y cancer: Memorándum de una Reunión de la OMS

ABSTRACT

There is increasing evidence from molecular biology and clinical investigations that infection with specific types of human papillomavirus (HPV) is associated with anogenital cancers, especially cancer of the cervix uteri. Human papillomavirus types 16 and 18 have been found in the majority of servical cancers investigated; specific viral mechanisms appear to be involved in the malignant conversion of these tumours. However, evidence from epidemiological investigations is still inconclusive. Concerted efforst to study the etiology and natural history of lower genital tract neoplasia and its association with HPV, together with the developement of vaccines against specific viral types, are needed in order to make it possible in the future to prevent cervical and other anogenital cancers