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Changes in RT-PCR-positive SARS-CoV-2 rates in adults and children according to the epidemic stages
Corinne Levy; Romain Basmaci; Philippe Bensaid; Cecile Bost bru; Edeline Coinde; Emmanuelle Dessioux; Cecile Fournial; Jean Gashignard; Herve Haas; Veronique Hentgen; Frederic Huet; Muriel Lalande; Alain Martinot; Charlotte Pons; Anne Sophie Romain; Nicoletta Magdalena Ursulescu; Francois Vie Le Sage; Josette Raymond; Stephane Bechet; Julie Toubiana; Robert Cohen.
Afiliação
  • Corinne Levy; ACTIV
  • Romain Basmaci; Hopital Louis Mourier, Colombe, France
  • Philippe Bensaid; Hopital Argenteuil, France
  • Cecile Bost bru; CHU Grenoble, France
  • Edeline Coinde; Hop Ajaccio,France
  • Emmanuelle Dessioux; Hop Pays du Mont Blanc, France
  • Cecile Fournial; Hop Nantes, France
  • Jean Gashignard; Hop Robert Debre, Paris, France
  • Herve Haas; Hop Nice, France
  • Veronique Hentgen; Versailles Hosp, France
  • Frederic Huet; Dijon hosp, France
  • Muriel Lalande; Montpellier Hosp, France
  • Alain Martinot; Lille hosp, France
  • Charlotte Pons; Avignon hosp, France
  • Anne Sophie Romain; Trousseau hosp, Paris, France
  • Nicoletta Magdalena Ursulescu; Belfort hosp, France
  • Francois Vie Le Sage; AFPA, France
  • Josette Raymond; Kremlin Bicetre hosp, France
  • Stephane Bechet; ACTIV
  • Julie Toubiana; Necker hosp, Paris, France
  • Robert Cohen; ACTIV
Preprint em Inglês | medRxiv | ID: ppmedrxiv-20098863
ABSTRACT
AimTo describe the trends of RT-PCR positive SARS-CoV-2 rates in children and adults according to the time of COVID-19 epidemic. MethodsIn this prospective multicenter study involving 45 pediatric units, we collected the results of nasopharyngeal swabs in France from March 2, 2020 to April 26, 2020. ResultsDuring the study period, 52,588 RT-PCR tests for SARS-CoV-2 were performed, 6,490 in children and 46,098 in adults. The risk ratio of RT-PCR positive SARS-CoV-2 tests for adults compared to children was 3.5 (95% CI [3.2;3.9]) for the whole study period. These rates varied according to the time of the epidemic and were higher at the peak. The lower rates of positive test in children persisted during the surveillance period but varied according to the time in the epidemic. ConclusionThe rate of positive RT-PCR positive SARS-CoV-2 tests for children was always less than that for adults but vary according to the epidemic stage.
Licença
cc_by_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo observacional / Estudo prognóstico Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo observacional / Estudo prognóstico Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
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