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The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study
Trystan Leng; Connor White; Joe Hilton; Adam J Kucharski; Lorenzo Pellis; Helena Stage; Nicholas G Davies; Matt J Keeling; Stefan Flasche.
Afiliação
  • Trystan Leng; University of Warwick
  • Connor White; University of Warwick
  • Joe Hilton; University of Warwick
  • Adam J Kucharski; London School of Hygiene & Tropical Medicine
  • Lorenzo Pellis; The University of Manchester
  • Helena Stage; University of Manchester
  • Nicholas G Davies; London School of Hygiene and Tropical Medicine
  • Matt J Keeling; University of Warwick
  • Stefan Flasche; LSHTM
Preprint em En | PREPRINT-MEDRXIV | ID: ppmedrxiv-20123448
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ABSTRACT
BackgroundDuring the Covid-19 lockdown, contact clustering in social bubbles may allow extending contacts beyond the household at minimal additional risk and hence has been considered as part of modified lockdown policy or a gradual lockdown exit strategy. We estimated the impact of such strategies on epidemic and mortality risk using the UK as a case study. MethodsWe used an individual based model for a synthetic population similar to the UK, that is stratified into transmission risks from the community, within the household and from other households in the same social bubble. The base case considers a situation where non-essential shops and schools are closed, the secondary household attack rate is 20% and the initial reproduction number is 0.8. We simulate a number of strategies including variations of social bubbles, i.e. the forming of exclusive pairs of households, for particular subsets of households (households including children and single occupancy households), as well as for all households. We test the sensitivity of the results to a range of alternative model assumptions and parameters. ResultsClustering contacts outside the household into exclusive social bubbles is an effective strategy of increasing contacts while limiting some of the associated increase in epidemic risk. In the base case scenario social bubbles reduced cases and fatalities by 17% compared to an unclustered increase of contacts. We find that if all households were to form social bubbles the reproduction number would likely increase to 1.1 and therefore beyond the epidemic threshold of one. However, strategies that allow households with young children or single occupancy households to form social bubbles only increased the reproduction number by less than 10%. The corresponding increase in morbidity and mortality is proportional to the increase in the epidemic risk but is largely focussed in older adults independently of whether these are included in the social bubbles. ConclusionsSocial bubbles can be an effective way of extending contacts beyond the household limiting the increase in epidemic risk, if managed appropriately.
Licença
cc_by_nc_nd
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-MEDRXIV Tipo de estudo: Experimental_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-MEDRXIV Tipo de estudo: Experimental_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Preprint