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Mutational landscape and dominant lineages in the SARS-CoV-2 infections in the state of Telangana, India
Asmita Gupta; Radhakrishnan Sabarinathan; Pratyusha Bala; Vinay Donipadi; Divya Vashisht; Madhumohan Rao Katika; Manohar Kandakatla; Debashis Mitra; Ashwin Dalal; Murali Dharan Bashyam.
Afiliação
  • Asmita Gupta; Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
  • Radhakrishnan Sabarinathan; TIFR - National Centre for Biological Sciences, Bengaluru, India
  • Pratyusha Bala; Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
  • Vinay Donipadi; Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
  • Divya Vashisht; Centre for DNA Fingerprinting and Diagnostics, Hyderabad
  • Madhumohan Rao Katika; Nizam's Institute of Medical Sciences, Hyderabad, India
  • Manohar Kandakatla; Nizam's Institute of Medical Sciences, Hyderabad, India
  • Debashis Mitra; Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
  • Ashwin Dalal; Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
  • Murali Dharan Bashyam; Centre for DNA Fingerprinting and Diagnostics,, Hyderabad, India
Preprint em Inglês | medRxiv | ID: ppmedrxiv-20180810
ABSTRACT
The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing COVID-19 has rapidly turned into a pandemic, infecting millions and causing ~7 million deaths across the globe. In addition to studying the mode of transmission and evasion of host immune system, analysing the viral mutational landscape constitutes an area under active research. The latter is expected to impart knowledge on the emergence of different clades, subclades, viral protein functions and protein-protein and protein-RNA interactions during replication/transcription cycle of virus and response to host immune checkpoints. In this study we have attempted to bring forth the viral genomic variants defining the major clade(s) as identified from samples collected from the state of Telangana, India.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
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