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Occupational and environmental exposure to SARS-CoV-2 in and around infected mink farms
Myrna M.T. de Rooij; Renate Hakze-Van der Honing; Marcel Hulst; Frank Harders; Marc Engelsma; Wouter van de Hoef; Kees Meliefste; Sigrid Nieuwenweg; Bas Oude Munnink; Isabella van Schothorst; Reina Sikkema; Arco van der Spek; Marcel Spierenburg; Jack Spithoven; Ruth Bouwstra; Robert-Jan Molenaar; Marion Koopmans; Arjan Stegeman; Wim H.M. Van der Poel; Lidwien A.M. Smit.
Afiliação
  • Myrna M.T. de Rooij; Utrecht University
  • Renate Hakze-Van der Honing; Wageningen Bioveterinary Research
  • Marcel Hulst; Wageningen Bioveterinary Research
  • Frank Harders; Wageningen Bioveterinary Research
  • Marc Engelsma; Wageningen Bioveterinary Research
  • Wouter van de Hoef; Utrecht University
  • Kees Meliefste; Utrecht University
  • Sigrid Nieuwenweg; Utrecht University
  • Bas Oude Munnink; ErasmusMC
  • Isabella van Schothorst; Utrecht University
  • Reina Sikkema; Erasmus MC
  • Arco van der Spek; Netherlands Food and Consumer Product Safety Authority
  • Marcel Spierenburg; Netherlands Food and Consumer Product Safety Authority
  • Jack Spithoven; Utrecht University
  • Ruth Bouwstra; GD Animal Health
  • Robert-Jan Molenaar; GD Animal Health
  • Marion Koopmans; Erasmus Medical Center
  • Arjan Stegeman; Utrecht University
  • Wim H.M. Van der Poel; Wageningen University and Research
  • Lidwien A.M. Smit; Utrecht University
Preprint em Inglês | medRxiv | ID: ppmedrxiv-20248760
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ABSTRACT
Unprecedented SARS-CoV-2 infections in farmed minks raised immediate concerns regarding human health which initiated intensive environmental investigations. Air sampling was performed in infected mink farms, at farm premises and at residential sites. A range of other environmental samples were collected from minks housing units including bedding material. Inside the farms, high levels of SARS-CoV-2 RNA were found in airborne dust, on surfaces, and on various other environmental matrices. This warns for occupational exposure which was substantiated by considerable SARS-CoV-2 RNA concentrations in personal air samples. Dispersion of SARS-CoV-2 to outdoor air was found to be limited and SARS-CoV-2 RNA was not detected in air samples collected beyond farm premises, implying a negligible environmental exposure risk for nearby communities. Our occupational and environmental risk assessment is in line with whole genome sequences analyses showing mink-to-human transmission in farm workers, but no indications for direct zoonotic transmission events to nearby communities.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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