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OpenSAFELY NHS Service Restoration Observatory 1: describing trends and variation in primary care clinical activity for 23.3 million patients in England during the first wave of COVID-19
Helen J Curtis; Brian MacKenna; Richard Croker; Alex J Walker; Peter Inglesby; Jessica Morley; Amir Mehrkar; Caroline E Morton; Seb Bacon; George Hickman; Chris Bates; David Evans; Tom Ward; Jonathan Cockburn; Simon Davy; Krishnan T. Bhaskaran; Anna Schultze; Christopher T. Rentsch; Elizabeth J Williamson; Will Hulme; Helen I McDonald; Laurie Tomlinson; Kevin Wing; Rohini I Mathur; Harriet Forbes; Angel Wong; Rosalind M Eggo; Henry Drysdale; John Parry; Frank Hester; Sam Harper; Ian J Douglas; Stephen Evans; Liam Smeeth; Ben Goldacre.
Afiliação
  • Helen J Curtis; University of Oxford
  • Brian MacKenna; University of Oxford
  • Richard Croker; University of Oxford
  • Alex J Walker; University of Oxford
  • Peter Inglesby; University of Oxford
  • Jessica Morley; University of Oxford
  • Amir Mehrkar; University of Oxford
  • Caroline E Morton; University of Oxford
  • Seb Bacon; University of Oxford
  • George Hickman; University of Oxford
  • Chris Bates; TPP
  • David Evans; University of Oxford
  • Tom Ward; University of Oxford
  • Jonathan Cockburn; TPP
  • Simon Davy; University of Oxford
  • Krishnan T. Bhaskaran; London School of Hygiene and Tropical Medicine
  • Anna Schultze; LSHTM
  • Christopher T. Rentsch; US Department of Veterans Affairs, London School of Hygiene and Tropical Medicine
  • Elizabeth J Williamson; LSHTM
  • Will Hulme; University of Oxford
  • Helen I McDonald; London School of Medicine and Tropical Medicine
  • Laurie Tomlinson; LSHTM
  • Kevin Wing; LSHTM
  • Rohini I Mathur; London School of Hygiene and Tropical Medicine
  • Harriet Forbes; LSHTM
  • Angel Wong; London School of Hygiene and Tropical Medicine
  • Rosalind M Eggo; LSHTM
  • Henry Drysdale; University of Oxford
  • John Parry; TPP
  • Frank Hester; TPP
  • Sam Harper; TPP
  • Ian J Douglas; LSHTM
  • Stephen Evans; LSHTM
  • Liam Smeeth; LSHTM
  • Ben Goldacre; University of Oxford
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21249352
ABSTRACT
BackgroundThe COVID-19 pandemic has disrupted healthcare activity globally. The NHS in England stopped most non-urgent work by March 2020, but later recommended that services should be restored to near-normal levels before winter where possible. The authors are developing the OpenSAFELY NHS Service Restoration Observatory, using data to describe changes in service activity during COVID-19, and reviewing signals for action with commissioners, researchers and clinicians. Here we report phase one generating, managing, and describing the data. ObjectiveTo describe the volume and variation of coded clinical activity in English primary care across 23.8 million patients records, taking respiratory disease and laboratory procedures as key examples. MethodsWorking on behalf of NHS England we developed an open source software framework for data management and analysis to describe trends and variation in clinical activity across primary care EHR data on 23.8 million patients; and conducted a population cohort-based study to describe activity using CTV3 coding hierarchy and keyword searches from January 2019-September 2020. ResultsMuch activity recorded in general practice declined to some extent during the pandemic, but largely recovered by September 2020, with some exceptions. There was a large drop in coded activity for commonly used laboratory tests, with broad recovery to pre-pandemic levels by September. One exception was blood coagulation tests such as International Normalised Ratio (INR), with a smaller reduction (median tests per 1000 patients in 2020 February 8.0; April 6.2; September 7.0). The overall pattern of recording for respiratory symptoms was less affected, following an expected seasonal pattern and classified as "no change" from the previous year. Respiratory tract infections exhibited a sustained drop compared with pre-pandemic levels, not returning to pre-pandemic levels by September 2020. Various COVID-19 codes increased through the period. We observed a small decline associated with high level codes for long-term respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. Asthma annual reviews experienced a small drop but since recovered, while COPD annual reviews remain below baseline. ConclusionsWe successfully delivered an open source software framework to describe trends and variation in clinical activity across an unprecedented scale of primary care data. The COVD-19 pandemic led to a substantial change in healthcare activity. Most laboratory tests showed substantial reduction, largely recovering to near-normal levels by September 2020, with some important tests less affected. Records of respiratory infections decreased with the exception of codes related to COVID-19, whilst activity of other respiratory disease codes was mixed. We are expanding the NHS Service Restoration Observatory in collaboration with clinicians, commissioners and researchers and welcome feedback.
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Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Cohort_studies / Estudo observacional / Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Cohort_studies / Estudo observacional / Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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