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A novel variant of interest of SARS-CoV-2 with multiple spike mutations is identified from travel surveillance in Africa
Tulio de Oliveira; Silvia Lutucuta; John Nkengasong; Joana Morais; Joana Paula Paixao; Zoraima Neto; Pedro Afonso; Julio Miranda; Kumbelembe David; Luzia Ingles; Amilton Pereira Agostinho Paulo Raisa Rivas Carralero; Helga Reis Freitas; Franco Mufinda; Sofonias Kifle Tessema; Houriiyah Tegally; Emmanuel James San; Eduan Wilkinson; Jennifer Giandhari; Sureshnee Pillay; Marta Giovanetti; Yeshnee Naidoo; Lavanya Singh; Derek Tshiabuila; Darren Martin; Richard John Lessells.
Afiliação
  • Tulio de Oliveira; University of KwaZulu-Natal
  • Silvia Lutucuta; Ministry of Health of Angola
  • John Nkengasong; Africa Centres for Disease Control and Prevention (Africa CDC)
  • Joana Morais; Ministry of Health of Angola
  • Joana Paula Paixao; Ministry of Health of Angola
  • Zoraima Neto; Ministry of Health of Angola
  • Pedro Afonso; Ministry of Health of Angola
  • Julio Miranda; Ministry of Health of Angola
  • Kumbelembe David; Ministry of Health of Angola
  • Luzia Ingles; Ministry of Health of Angola
  • Amilton Pereira Agostinho Paulo Raisa Rivas Carralero; Ministry of Health of Angola
  • Helga Reis Freitas; Ministry of Health of Angola
  • Franco Mufinda; Ministry of Health of Angola
  • Sofonias Kifle Tessema; Africa Centres for Disease Control and Prevention (Africa CDC)
  • Houriiyah Tegally; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Emmanuel James San; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Eduan Wilkinson; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Jennifer Giandhari; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Sureshnee Pillay; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Marta Giovanetti; FioCruz Foundation
  • Yeshnee Naidoo; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Lavanya Singh; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Derek Tshiabuila; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
  • Darren Martin; University of Cape Town
  • Richard John Lessells; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at UKZN
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21254323
ABSTRACT
At the end of 2020, the Network for Genomic Surveillance in South Africa (NGS-SA) detected a SARS-CoV-2 variant of concern (VOC) in South Africa (501Y.V2 or PANGO lineage B.1.351)1. 501Y.V2 is associated with increased transmissibility and resistance to neutralizing antibodies elicited by natural infection and vaccination2,3. 501Y.V2 has since spread to over 50 countries around the world and has contributed to a significant resurgence of the epidemic in southern Africa. In order to rapidly characterize the spread of this and other emerging VOCs and variants of interest (VOIs), NGS-SA partnered with the Africa Centres for Disease Control and Prevention and the African Society of Laboratory Medicine through the Africa Pathogen Genomics Initiative to strengthen SARS-CoV-2 genomic surveillance across the region.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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