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SARS-CoV-2 variants of concern, variants of interest and lineage A.27 are on the rise in Cote d'Ivoire
Etilé Augustin Anoh; Grit Schubert; Oby Wayoro; Monemo Pacôme; Essia Belarbi; Andreas Sachse; Sébastien Calvignac-Spencer; Fabian Leendertz; Bamourou Diané; Chantal Akoua-Koffi.
Afiliação
  • Etilé Augustin Anoh; Centre Hospitalier Universitaire Bouaké, Côte d'Ivoire
  • Grit Schubert; Robert Koch-Institute, Berlin, Germany
  • Oby Wayoro; Centre Hospitalier Universitaire Bouaké, Côte d'Ivoire
  • Monemo Pacôme; Centre Hospitalier Universitaire Bouaké, Côte d'Ivoire
  • Essia Belarbi; Robert Koch-Institute, Berlin, Germany
  • Andreas Sachse; Robert Koch-Institute, Berlin, Germany
  • Sébastien Calvignac-Spencer; Robert Koch-Institute, Berlin, Germany
  • Fabian Leendertz; Robert Koch-Institute, Berlin, Germany
  • Bamourou Diané; Centre Hospitalier Universitaire Bouaké, Côte d'Ivoire
  • Chantal Akoua-Koffi; Centre Hospitalier Universitaire Bouaké, Côte dIvoire
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21256282
ABSTRACT
SARS-CoV-2 variants of concern (VOC) and variants of interest (VOI) are heavily altering the COVID-19 pandemics course due to their increased transmissibility, virulence and immune escape abilities. Data on their spread in western sub-Saharan Africa is however still scarce. We therefore sequenced viral genomes from SARS-CoV-2 cases identified in central and northern Cote dIvoire between May 2020 and March 2021. We report the introduction of VOC B.1.1.7 as early as mid-January 2021, followed by detection of a single case of VOC B.1.351, as well as VOI B.1.525. Since early 2021 VOC/VOI are gradually dominating the SARS-CoV-2 virus pool in Cote dIvoire, as seen in other regions of the world. Intriguingly, we also find that another lineage, A.27, has also been on the rise over the same period. In sum, this study highlights again the extremely rapid local diffusion of VOC, VOI and possibly A.27, and the importance of further reinforcing capacities for genomic surveillance on the African continent.
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Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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