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COVID-19 in twins: What can we learn from them
Mateus V. Castro; Monize V. R. Silva; Michel S. Naslavsky; Keity S. Santos; Jhosiene Y. Magawa; Edecio Cunha-Neto; Maria Rita Passos Bueno; Mayana Zatz.
Afiliação
  • Mateus V. Castro; Human Genome and Stem Cell Research Center, University of Sao Paulo, Sao Paulo, SP, Brazil.
  • Monize V. R. Silva; Human Genome and Stem Cell Research Center, University of Sao Paulo, Sao Paulo, SP, Brazil.
  • Michel S. Naslavsky; Human Genome and Stem Cell Research Center, University of Sao Paulo, Sao Paulo, SP, Brazil.
  • Keity S. Santos; Laboratorio de Imunologia, Instituto do Coracao (InCor), LIM19, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, (HCFMUSP), Sao Paul
  • Jhosiene Y. Magawa; Laboratorio de Imunologia, Instituto do Coracao (InCor), LIM19, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, (HCFMUSP), Sao Paul
  • Edecio Cunha-Neto; Laboratorio de Imunologia, Instituto do Coracao (InCor), LIM19, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, (HCFMUSP), Sao Paul
  • Maria Rita Passos Bueno; Human Genome and Stem Cell Research Center, University of Sao Paulo, Sao Paulo, SP, Brazil.
  • Mayana Zatz; Human Genome and Stem Cell Research Center, University of Sao Paulo, Sao Paulo, SP, Brazil.
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21263145
ABSTRACT
Investigations on the concordance in monozygotic (MZ) as compared to dizygotic (DZ) twins may reveal if there is a genetic component increasing the susceptibility or resistance against an infectious disease. Here, we compared the concordance rates of SARS-CoV-2 infection in MZ versus DZ young twins who shared the same bedrooms and were equally exposed to the virus. The concordance rate was higher in the MZ group supporting a complex multifactorial inheritance responsible for SARS-Cov-2 infection.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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