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Waning antibody levels after vaccination with mRNA BNT162b2 and inactivated CoronaVac COVID-19 vaccines in Hong Kong blood donors
Shirley LL Kwok; Samuel MS Cheng; Jennifer NS Leung; Kathy Leung; Cheuk-Kwong Lee; Joseph T Wu; Joseph Sriyal Malik Peiris.
Afiliação
  • Shirley LL Kwok; The University of Hong Kong
  • Samuel MS Cheng; The University of Hong Kong
  • Jennifer NS Leung; Hong Kong Blood Transfusion Service
  • Kathy Leung; The University of Hong Kong
  • Cheuk-Kwong Lee; Hong Kong Blood Transfusion Service
  • Joseph T Wu; The University of Hong Kong
  • Joseph Sriyal Malik Peiris; University of Hong Kong
Preprint em En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21267330
ABSTRACT
Both inactivated vaccine (CoronaVac; Sinovac) and mRNA vaccine (Comirnaty/BNT162b2; Fosun-Pharma/BioNTech) are available in Hong Kongs COVID-19 Vaccination Programme. We reported waning antibody levels by enzyme-linked immunosorbent assays (ELISA) and surrogate virus neutralization test (sVNT) among 850 fully vaccinated blood donors (i.e., received two doses). The BNT162b2 groups antibody levels remain over the 50% protection threshold within six months, and the CoronaVacs groups median antibody levels begin to fall below the 50% protection threshold two months after vaccination.
Licença
cc_by_nc_nd
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-MEDRXIV Tipo de estudo: Experimental_studies / Rct Idioma: En Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-MEDRXIV Tipo de estudo: Experimental_studies / Rct Idioma: En Ano de publicação: 2021 Tipo de documento: Preprint