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Co-infection with SARS-COV-2 Omicron and Delta Variants Revealed by Genomic Surveillance
Rebecca J Rockett; Jenny Draper; Mailie Gall; Eby M Sim; Alicia Arnott; Jessica E Agius; Jessica Johnson-Mackinnon; Elena Martinez; Alexander P Drew; Clement Lee; Christine Ngo; Marc Ramsperger; Andrew N Ginn; Qinning Wang; Michael Fennell; Danny Ko; Linda Huston; Lukas Kairaitis; Edward C Holmes; Matthew N O'Sullivan; Sharon C-A Chen; Jen Kok; Dominic E Dwyer; Vitali Sintchenko.
Afiliação
  • Rebecca J Rockett; Sydney Institute for Infectious Diseases, University of Sydney, Sydney, New South Wales, Australia
  • Jenny Draper; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Mailie Gall; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Eby M Sim; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Alicia Arnott; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Jessica E Agius; Sydney Institute for Infectious Diseases, University of Sydney, Sydney, New South Wales, Australia
  • Jessica Johnson-Mackinnon; Sydney Institute for Infectious Diseases, University of Sydney, Sydney, New South Wales, Australia
  • Elena Martinez; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Alexander P Drew; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Clement Lee; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Christine Ngo; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Marc Ramsperger; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Andrew N Ginn; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Qinning Wang; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Michael Fennell; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Danny Ko; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Linda Huston; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Lukas Kairaitis; Renal Services, Blacktown Hospital, Western Sydney Local Health District, Sydney, New South Wales, Australia
  • Edward C Holmes; School of Life & Environmental Sciences and School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia
  • Matthew N O'Sullivan; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Sharon C-A Chen; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Jen Kok; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Dominic E Dwyer; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology Wes
  • Vitali Sintchenko; Sydney Institute for Infectious Diseases, University of Sydney, Sydney, New South Wales, Australia
Preprint em Inglês | medRxiv | ID: ppmedrxiv-22270755
ABSTRACT
We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating locally at the time of detection. Amplicon- and probe-based sequencing using short- and long-read technologies identified and quantified Omicron and Delta subpopulations in respiratory samples from the two patients. These findings highlight the importance of genomic surveillance in vulnerable populations.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2022 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Idioma: Inglês Ano de publicação: 2022 Tipo de documento: Preprint
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