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Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control study, Germany, June 2021 to January 2022
Anna Stoliaroff; Caroline Peine; Tim Herath; Johannes Lachmann; Achim Doerre; Delphine Perriat; Andreas Nitsche; Janine Michel; Thomas Rinner; Daniel Stern; Fridolin Treindl; Natalie Hofmann; Marica Grossegesse; Claudia Kohl; Annika Brinkmann; Tanja Meyer; Brigitte Dorner; Sascha Hein; Laura Werel; Eberhard Hildt; Sven Glaeser; Helmut Schuehlen; Caroline Isner; Alexander Peric; Ammar Ghouzi; Annette Reichardt; Matthias Janneck; Guntram Lock; Lars Schaade; Ole Wichmann; Thomas Harder.
Afiliação
  • Anna Stoliaroff; Robert Koch-Institute
  • Caroline Peine; Robert Koch-Institute
  • Tim Herath; Robert Koch-Institute
  • Johannes Lachmann; Robert Koch-Institute
  • Achim Doerre; Robert Koch-Institute
  • Delphine Perriat; Robert Koch-Institute
  • Andreas Nitsche; Robert Koch Institute
  • Janine Michel; Robert Koch-Institute
  • Thomas Rinner; Robert Koch-Institute
  • Daniel Stern; Robert Koch-Institute
  • Fridolin Treindl; Robert Koch-Institute
  • Natalie Hofmann; Robert Koch-Institute
  • Marica Grossegesse; Robert Koch Institute
  • Claudia Kohl; Robert Koch-Institute
  • Annika Brinkmann; Robert Koch-Institute
  • Tanja Meyer; Robert Koch-Institute
  • Brigitte Dorner; Robert Koch-Institute
  • Sascha Hein; Paul-Ehrlich-Institute
  • Laura Werel; Paul-Ehrlich-Institute
  • Eberhard Hildt; Paul-Ehrlich-Institute
  • Sven Glaeser; Vivantes Netzwerk fuer Gesundheit GmbH
  • Helmut Schuehlen; Vivantes Netzwerk fuer Gesundheit GmbH
  • Caroline Isner; Vivantes Netzwerk fuer Gesundheit GmbH
  • Alexander Peric; Vivantes Netzwerk fuer Gesundheit GmbH
  • Ammar Ghouzi; Schoen Klinik Duesseldorf
  • Annette Reichardt; Helios Klinikum Berlin-Buch
  • Matthias Janneck; Albertinen Krankenhaus Hamburg
  • Guntram Lock; Albertinen Krankenhaus Hamburg
  • Lars Schaade; Robert Koch-Institute
  • Ole Wichmann; Robert Koch-Institute
  • Thomas Harder; Robert Koch-Institute
Preprint em Inglês | medRxiv | ID: ppmedrxiv-22276303
ABSTRACT
We included 852 patients in a prospectively recruiting multicenter matched case-control study in Germany to assess vaccine effectiveness (VE) in preventing COVID-19-associated hospitalization (Delta-variant dominance). Two-dose VE was 89% (95%CI 84-93%) overall, 79% in patients with >2 comorbidities and 77% in adults aged 60-75 years. A third dose increased VE to >93% in all patient-subgroups.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo observacional Idioma: Inglês Ano de publicação: 2022 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo observacional Idioma: Inglês Ano de publicação: 2022 Tipo de documento: Preprint
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