T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy
(East. Mediterr. health j).
em Inglês
| WHO IRIS
| ID: who-117702
Biblioteca responsável:
CH1.1
ABSTRACT
This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysis
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Base de dados:
WHO IRIS
Assunto principal:
Linfócitos T
/
Diálise Renal
/
Interferon gama
/
Interleucina-10
/
Selectina E
/
Creatinina
/
Diabetes Mellitus Tipo 2
/
Nefropatias Diabéticas
/
Endotélio
Idioma:
Inglês
Revista:
East. Mediterr. health j
Ano de publicação:
2009