Prevalence of coeliac disease among adult patients with autoimmune hypothyroidism in Jordan
(East. Mediterr. health j).
em Inglês
| WHO IRIS
| ID: who-118623
Biblioteca responsável:
CH1.1
ABSTRACT
The prevalence of coeliac disease among patients with autoimmune hypothyroidism has not been studied before in Jordan and other Arab countries. A cross-sectional record-based review was made of all adult autoimmune hypothyroidism patients who attended a referral centre in Jordan, during an 8-month period. Coeliac disease in these patients was diagnosed by the attending physician based on positive serological tests for anti-endomysial antibodies IgA and IgG followed by duodenal biopsy to confirm the diagnosis of coeliac disease. Of 914 patients recruited, 117 [12.8%] were seropositive for coeliac disease. Of 87 seropositive patients who underwent duodenal biopsy, 39 had positive histological findings of coeliac disease [44.8%]. Extrapolating from these findings the overall rate of coeliac disease among autoimmune hypothyroidism patients was estimated to be 5.7%. In multivariate logistic regression coeliac disease was significantly associated with older age [> 40 years], presence of other autoimmune diseases, vitamin B12 deficiency and anaemia
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Base de dados:
WHO IRIS
Idioma:
Inglês
Revista:
East. Mediterr. health j
Ano de publicação:
2014