Red cell glucose-6-phosphate dehydrogenase phenotypes in Iraq
(East. Mediterr. health j).
em Inglês
| WHO IRIS
| ID: who-119135
Biblioteca responsável:
CH1.1
ABSTRACT
We attempted to characterize biochemically glucose-6-phosphate dehydrogenase [G6PD] variants in Iraqi individuals. Thus 758 healthy Iraqi males aged 18-60 years were randomly selected and 46 [6.1%] were G6PD deficient. Although the predominant non-deficient G6PD phenotype was G6PD B [92.6%], G6PD A+ was found in polymorphic frequency [1.3%]. In the deficient group, 31 cases were fully characterized, including 17 cases with features consistent with G6PD Mediterranean variant, while 12 had other biochemical features and were labelled as non-Mediterranean variant. The remaining two deficient cases were characterized as G6PD A- variant. The presence of a significant number of non-Mediterranean variant was unexpected and may be related to the more heterogeneous background of the Iraqi people
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Base de dados:
WHO IRIS
Assunto principal:
Fenótipo
/
Polimorfismo Genético
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Estudos de Casos e Controles
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Epidemiologia Molecular
/
Eletroforese em Acetato de Celulose
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Eritrócitos
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Favismo
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Frequência do Gene
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Glucosefosfato Desidrogenase
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Deficiência de Glucosefosfato Desidrogenase
Idioma:
Inglês
Revista:
East. Mediterr. health j
Ano de publicação:
2002