A Case of Acantholytic Squamous Cell Carcinoma on a Male Areola:An Uncommon Histologic Variant at a Rare Location / 대한피부과학회지
Korean Journal of Dermatology
; : 308-312, 2023.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-1002187
Biblioteca responsável:
WPRO
ABSTRACT
The areola is a rare location for squamous cell carcinoma (SCC) because sunlight exposure, the main risk factor for SCC, is unusual on it. Acantholytic SCC (ASCC) is a rare histologic variant of SCC, characterized by pseudoglandular appearance with acantholytic tumor cells. A 59-year-old male presented a painful erythematous papule on his right areola. He had a history of psoralen ultraviolet A phototherapy for psoriasis in his 20s. Biopsy revealed an epithelial tumor and pseudoglandular structures with acantholytic tumor cells. In immunohistochemistry, cytokeratin 5/6, epithelial membrane antigen, and p63 were positive, while cytokeratin 7, carcinoembryonic antigen, S-100, and estrogen and progesterone receptors were negative. Periodic acid-Schiff stain was negative. Ki-67 labeling index was 79.7%. The final diagnosis was ASCC of the areola. After wide local excision, recurrence have not been reported. Here, we report a case of ASCC on the areola, focusing on its rare histologic variant and uncommon location.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Korean Journal of Dermatology
Ano de publicação:
2023
Tipo de documento:
Artigo