More microinvasive foci in larger tumours of breast ductal carcinoma in situ
Singapore medical journal
; : 493-496, 2023.
Article
em En
| WPRIM
| ID: wpr-1007333
Biblioteca responsável:
WPRO
ABSTRACT
INTRODUCTION@#Microinvasion (Mi) is often thought to be an interim stage between ductal carcinoma in situ (DCIS) and invasive ductal carcinoma. This study aimed to investigate the potential influence of Mi on survival and assess its correlations with clinicopathological parameters, prognosis and molecular markers.@*METHODS@#The number of Mi foci in a cohort of 66 DCIS-Mi cases was assessed from haematoxylin and eosin-stained sections. Disease-free survival, clinicopathological parameters and biomarker expression were correlated with the number of Mi foci.@*RESULTS@#Higher numbers of Mi foci were found in larger tumours (P = 0.031).@*CONCLUSION@#Greater extent of DCIS is associated with multifocal Mi.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prognóstico
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Neoplasias da Mama
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Carcinoma Ductal de Mama
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Carcinoma Intraductal não Infiltrante
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Intervalo Livre de Doença
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Intervalo Livre de Progressão
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Invasividade Neoplásica
Limite:
Female
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Humans
Idioma:
En
Revista:
Singapore medical journal
Ano de publicação:
2023
Tipo de documento:
Article