Current immune therapeutic strategies in advanced or metastatic non-small cell lung cancer / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 1765-1782, 2023.
Article
em En
| WPRIM
| ID: wpr-1007580
Biblioteca responsável:
WPRO
ABSTRACT
Immune escape mechanisms in non-small cell lung cancer (NSCLC) can disrupt every step of the anti-cancer immune response. In recent years, an increased understanding of the specific mechanisms fueling immune escape has allowed for the development of numerous immunotherapeutic treatments that have been introduced into the clinical practice. The advent of immunotherapy has dramatically changed the current treatment landscape of advanced or metastatic NSCLC because of its durable efficacy and manageable toxicity. In this review, we will first present a brief overview of recent evidence on immune escape mechanisms in NSCLC. We will then discuss the current promising immunotherapeutic strategies in advanced or metastatic NSCLC tumors.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Carcinoma Pulmonar de Células não Pequenas
/
Imunoterapia
/
Neoplasias Pulmonares
Limite:
Humans
Idioma:
En
Revista:
Chinese Medical Journal
Ano de publicação:
2023
Tipo de documento:
Article