Effect of Bigelovii A on hepatocellular carcinoma by regulating SHP and STAT signaling pathway / 中国药理学通报

ABSTRACT

Aim To investigate the effect of Bigelovii A on HepG2 cell apoptosis and its possible mechanism. Methods MTT assay was used to determine the inhibitory effect of Bigelovii A on HepG2 cells. Flow cytometry was performed to detect apoptosis. Western blot was applied to detect the expression of proteins of STAT pathway. Results BA (20 μmol L