Effects of compatibility on pharmacokinetics of mangiferin in INS-1 cells and its intracellular distribution / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 579-584, 2021.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-1014401
Biblioteca responsável:
WPRO
ABSTRACT
Aim To investigate the effect of compatibility of phellodendron amurense on the pharmacokinetics of mangiferin(MGF) in INS-1 cells, and the distribution of mangiferin in normal and oxidatively damaged INS-1 cells. Methods INS-1 cells were administered in equal doses of mangiferin, anemarrhena and anemarrhena-phellodendron herb pair. LC-MS/MS was used to determine the content of MGF in INS-1 cells. The normal and model groups (INS-1 cells were treated with 140 μmol · L
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2021
Tipo de documento:
Artigo