Research progress on the role of thrombospondin 2 in malignant tumors / 基础医学与临床
Basic & Clinical Medicine
; (12): 1881-1885, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1018558
Biblioteca responsável:
WPRO
ABSTRACT
Thrombospondin 2(THBS2)is a matrix cell calcium-binding glycoprotein that interacts with a variety of growth factors,receptors,matrix molecules or proteases on the extracellular matrix and cell surface.THBS2 can be activated by N6-methyladenosyl RNA methylase,and mediates tumor proliferation,migration and invasion by re-modeling the tumor microenvironment and participating in multiple cell signaling pathways.THBS2 could be used as a diagnostic and prognostic indicator for a variety of tumors,and is expected to become a new target for malignant tumor treatment.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Basic & Clinical Medicine
Ano de publicação:
2023
Tipo de documento:
Article