A Case of del(16)(q22) in a Patient with Acute Myeloid Leukemia with Complex Karyotype / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 329-333, 2010.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-102103
Biblioteca responsável:
WPRO
ABSTRACT
Inversion of chromosome 16 [inv(16)(p13.1q22)] and t(16;16)(p13.1;q22) are associated with acute myelomonocytic leukemia (AMML) with eosinophilia and a favorable prognosis. On the other hand, patients with del(16)(q22) usually present with MDS or chronic myelomonocytic leukemia (CMML), which can evolve to AMML without eosinophilia, and this chromosomal aberration is associated with older age, a complex karyotype, and a poor prognosis. We report a case of AML with del(16)(q22) which showed a complex karyotype, absence of eosinophilia in bone marrow study and a poor response to chemotherapy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Cromossomos Humanos Par 16
/
Leucemia Mieloide Aguda
/
Daunorrubicina
/
Deleção Cromossômica
/
Hibridização in Situ Fluorescente
/
Citarabina
/
Quimioterapia Combinada
/
Células Precursoras de Monócitos e Macrófagos
/
Cariotipagem
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2010
Tipo de documento:
Artigo