Research progress in the immune escape mechanism of Trichinella spiralis / 中国人兽共患病学报
Chinese Journal of Zoonoses
; (12): 70-75, 2024.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-1024891
Biblioteca responsável:
WPRO
ABSTRACT
Trichinosis is a global food-borne zoonotic parasitic disease caused by Trichinella spiralis(T.spiralis),which causes serious harm to animal production,and the public health safety of humans and animals.T.spiralis has a complex devel-opment history,and its entire life cycle is completed in the same host.To coexist with the host,it has evolved various immune escape mechanisms for avoiding immune clearance by the host,thus establishing long-term chronic infection.In this study,to aid in understanding the pathogenic mechanism of T.spiralis,the immune escape mechanism of Trichinella is discussed from three aspectsthe molecular role of antigens in various stages,the immune regulatory effect on the host,and the formation of cysts to generate immune isolation.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Zoonoses
Ano de publicação:
2024
Tipo de documento:
Artigo