Study of the sign of color doppler ultrasound diagnosis of thyroid micro-carcinoma / 中国现代医生

ABSTRACT

Objective To evaluate the diagnostic value of color Doppler ultrasound (CDUS ) in thyroid microcarcinom (TMC). Methods With surgical pathologic examination results as the gold standard, 114 thyroid lumps were divided in-to observation group (including 51 pieces of TMC lump)and control group (including 63 pieces of benign lump). The sign of CDUS were analyzed retrospectively in the two groups. Logistic regression analysis was used to screen the CDUS characteristic parameters which associated with TMC and established TMC diagnosis prediction model. Results The percentage of anteroposterior and transverse diameter ratio(A/T)>1, unclear edge, hypoechoic nodules, absent halo sign, micro calcifications, resistance index(RI)>0.70 of the observation group were higher than those of the control group(P<0.01). Blood flow signal distribution in the 2 groups were different significantly (P<0.01). Multi-factor stepwise Logistic regression analysis results show that the absent halo sign, unclear edge, RI>0.70, hypoechoic nodules and blood flow signal ≤2 were associated with TMC (P<0.05). The above five indexes were used to establish regression model to pre-dict TMC and the sensitivity, specific degrees and accuracy were 93.75%, 90.90%, 92.11%. Conclusion The Logistic regression model with echo, edge, RI and blood flow signal in CDUS can be helpful for early accurate diagnosis of TMC.