The cerebral perfusion abnormal analysis of arterial sclerotic stenosis degree:based on CT perfusion and DSA image / 中风与神经疾病杂志

ABSTRACT

@#Objective To investigate the abnormal cerebral perfusion of unilateral ICA and VBA sclerotic stenosis by CT perfusion and DSA image.Methods Among 219 patients with ICS,the imaging (CTP,DSA) and clinical data from 120 patients with unilateral ICA sclerotic stenos(67 patients)and VBA sclerotic stenosis 53 patients were analyzed retrospectively.The degree of ICA sclerotic stenosis and collateral circulation were determined according to DSA results.Univariate analysis was used to explore the effects of stenosis degree of ICA and VBA sclerosis,establishment of collateral circulation and stroke risk factors on cerebral perfusion.Results The degree of unilateral ICA and VBA sclerosis stenosis has a low-degree positive correlation with cerebral perfusion (r=0.249,P=0.042,P=0.025;r=0.381,P=0.005,P=0.007),which is statistically significant.The collateral circulation of unilateral ICA stenosis (13 cases of normal perfusion and 12 cases of hypoperfusion) was significantly different from cerebral perfusion (P=0.041).There was no statistical significance between abnormal CTP perfusion and stroke factors (P>0.05).Fifty three cases of VBA sclerosis stenosis (19 cases of low perfusion include VBA severe stenosis 5 and occlusion 14;34 cases of normal perfusion group include 22 cases of severe stenosis and 12 cases of occlusion).There was no statistical significance between the establishment of collateral circulation (23 cases in the normal perfusion group and 8 cases in the low perfusion group) and the influencing factors of stroke (P>0.05).Conclusion There was a low positive correlation between the degree of sclerotic stenosis of ICA and VBA and cerebral perfusion.The establishment of collateral circulation can improve the state of cerebral blood flow to a certain extent.