Quantitative Analysis of Tissue Injury after Minimally Invasive Total Hip Arthroplasty
Clinics in Orthopedic Surgery
; : 279-284, 2014.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-104729
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
We intended to clarify the hypothesis that minimally invasive total hip arthroplasty (MI-THA) leads to less tissue damage and inflammatory response than does conventional total hip arthroplasty (C-THA).METHODS:
We performed 30 cases of THA between September 2005 and May 2006 and evaluated these cases prospectively. We chose 15 MI-THA cases for the study group and another 15 C-THA cases for the control group. We checked skeletal muscle marker enzymes, such as serum creatinine kinase and aldolase, the pro-inflammatory cytokines, interleukin (IL)-6 and 8, and the anti-inflammatory cytokines, IL-10 and IL-1 receptor antagonist (ra) the day before surgery and at postoperative days 1, 7, and 14.RESULTS:
On postoperative days 1 and 3, the study group showed significantly lower serum creatinine kinase, IL-6, IL-10, and IL-1ra values than those in the control group. Additionally, IL-8 was significantly lower on day 7 after surgery.CONCLUSIONS:
These data show that MI-THA decreased the release of muscle marker enzymes due to tissue damage immediately after surgery and minimized the inflammatory response related to the surgery during the early postoperative period.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biomarcadores
/
Interleucina-8
/
Interleucina-6
/
Interleucina-10
/
Lesões dos Tecidos Moles
/
Procedimentos Cirúrgicos Minimamente Invasivos
/
Artroplastia de Quadril
/
Creatina Quinase
/
Proteína Antagonista do Receptor de Interleucina 1
/
Frutose-Bifosfato Aldolase
Limite:
Adulto
/
Idoso
/
Idoso, 80 anos ou mais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clinics in Orthopedic Surgery
Ano de publicação:
2014
Tipo de documento:
Artigo