Predicting Factors for Death from Other Causes in Patients with Localized Renal Cell Carcinoma
Korean Journal of Urology
; : 18-22, 2012.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-106970
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
To identify the predictors of death from other causes in patients with localized renal cell carcinoma (RCC). MATERIALS ANDMETHODS:
We identified 1,101 patients with pathologically confirmed T1 or T2 RCC with a follow-up duration of over 6 months. Survival according to the cause of death was evaluated by using the Kaplan-Meier analysis with log-rank test. Prognostic factors for death from other causes were assessed by multivariate analysis using the Cox proportional hazard regression model. Once the prognostic factors were identified, a risk-group variable was created by counting the number of unfavorable features present for each patient.RESULTS:
The median follow-up was 62 months, and RCC-related death occurred in 50 patients (4.5%), whereas death from other causes occurred in 47 (4.3%). Patients who died from other causes had a higher American Society of Anesthesiologist (ASA) score (26.1% vs. 10.2%; p=0.044), older age (63.4 years vs. 55.0 years; p<0.001), smaller mass size (5.1 cm vs. 7.9 cm; p<0.001), and lower nuclear grade (p=0.003). In the multivariate Cox regression analysis, older age, higher ASA score, and lower body mass index were independent factors predicting death from other causes in patients with localized RCC. On the basis of the number of risk factors for death from other causes, the 5-year other-cause-specific survival was 98.3% (0 risk factors), 84.7% (1 risk factor), and 67.6% (2 or 3 risk factors), respectively (p<0.001).CONCLUSIONS:
Older age, higher ASA score, and lower body mass index were independent predictors of death from other causes in patients with localized RCC.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Carcinoma de Células Renais
/
Índice de Massa Corporal
/
Análise Multivariada
/
Fatores de Risco
/
Seguimentos
/
Causas de Morte
/
Estimativa de Kaplan-Meier
/
Conduta Expectante
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Urology
Ano de publicação:
2012
Tipo de documento:
Artigo