Comparison of Urea Kinetic Modeling and Indices of Nutrition in Hemodialysis Patients / 대한신장학회잡지
Korean Journal of Nephrology
; : 445-454, 1999.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-108785
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVES:
Protein-calorie malnutrition has been shown to be prevalent among patients on long-term hemodialysis(HD) patients. And assessment of nutritional status of HD patients has assumed greater importance because of the association of protein- calorie malnutrition with increasing morbidity and mortality. So we observed the incidence and clinical effect of protein-calorie malnutrition, and we compared the indices of nutrition with dialysis adequacy utilizing urea kinetic modeling in HD patients.METHODS:
We performed a cross-sectional study in which eight parameters, based on anthropometry, blood chemistry and subjective symptoms, were scored according to the degree of abnormalities in 48 HD patients. A malnutrition index was derived from these scores. We also performed comparative analysis to identify significant correlations of the indices of urea kinetic modeling with the other parameters of nutritional status.RESULTS:
The malnutrition index classified 12(25 %) patients as normal, 28(58%) intermediately malnourished, and 8(17%) as severely malnourished. Malnutrition index showed a significant correlation with the body mass index(BMI), mid-arm circumference(MAC), mid-arm muscle area(MAMA), duration of HD, total lymphocyte count,trnsferrin. The malnutrition index also showed a significant correlation with renal creatinine clearance(Ccr), alkaline phosphatase. However, malnutrition index showed no meaningful correlation with TWR-Kt/V, TW-Kt/V, BUN, cholesterol,calcium, triglyceride. The value of Ccr was significantly lower in the severely malnourished and intermediately group than in the normal group.CONCLUSION:
In assessing the nutritional status of HD patients, body weight, MAC, MAMA, duration of HD, total lymphocyte count, transferrin, alkaline phosphatase and Ccr were considered useful parameters. No meaningful relationships between TW-Kt/V and malnutrition index or between NPCR (normalized protein catabolic rate) and malnutrition index were found in this cross-sectional study. As the number of patients with longer duration of HD or negligible Ccr has increased in the malnourished patients, regular monitoring of these parameters, especially TWR-Kt/V and residual renal function may be helpful to assess dialysis adequacy to keep good nutritional status of each HD patient.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Desnutrição e Deficiências Nutricionais
/
Obesidade
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Triglicerídeos
/
Ureia
/
Peso Corporal
/
Transferrina
/
Linfócitos
/
Química
/
Antropometria
/
Estado Nutricional
/
Incidência
/
Estudos Transversais
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Aspecto:
Determinantes sociais da saúde
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nephrology
Ano de publicação:
1999
Tipo de documento:
Artigo