Risk Factors Associated with Mortality in Emergency Surgery for Perforated Peptic Ulcer
Journal of the Korean Surgical Society
; : 373-378, 2004.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-109022
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Despite modern medication, peptic ulcer, patients often require emergency surgery for complications of peptic ulcer disease, and the mortality due to a perforated peptic ulcer still remains high. This retrospective study was conducted to evaluate the risk factors associated with mortality in patients undergoing surgery for a perforated peptic ulcer.METHODS:
Two hundred and four consecutive patients (mean age 45.8 years; range 15~0 years) who underwent emergency surgery for a perforated peptic ulcer at the National Medical Center, between January 1991 and December 2000, were reviewed.RESULTS:
The overall mortality rate was 5.9%. A univariate analysis of multiple clinical variables revealed old age (> or =65 years), duration of symptoms (> or =24 hours), NSAIDs or steroid use, comorbid disease, shock on admission, low hemoglobin ( or =20 mg%), higher creatinine (> or =1.5 mg%), gastric ulcer and simple closure to be significantly associated with mortality. However, a multivariate analysis showed that shock on admission, comorbid disease and old age (> or =65 years) were independent predictors of mortality.CONCLUSION:
Shock on admission, comorbid disease and old age should be considered as significant prognostic factors of emergency surgery for a perforated peptic ulcer, and a comorbid disease and age as non modifiable factors. For that reason, prompt resuscitation is considered as the most effective therapy for reducing the mortality due to peptic ulcer perforation.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Doenças do Sistema Digestório
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Péptica
/
Úlcera Péptica Perfurada
/
Ressuscitação
/
Choque
/
Úlcera Gástrica
/
Anti-Inflamatórios não Esteroides
/
Análise Multivariada
/
Estudos Retrospectivos
/
Fatores de Risco
/
Mortalidade
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Surgical Society
Ano de publicação:
2004
Tipo de documento:
Artigo