Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor
Journal of Veterinary Science
; : 257-260, 2017.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-109771
Biblioteca responsável:
WPRO
ABSTRACT
This is the first case report to describe the tumor regressive effect of systemic human neural stem cell (NSC)/5-fluorocytosine (5-FC) therapy on canine metastatic lung tumor. The therapeutic effects appeared approximately two weeks after 5-FC administration. Thoracic radiographs revealed a reduced number of lung nodules and decreased nodule size. However, there were no significant antitumor effects on primary lesions in abdominal organs. In conclusion, human NSC/5-FC prodrug therapy can secure patient quality of life with the same or more therapeutic effects and fewer side effects than other recommended chemotherapies.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Qualidade de Vida
/
Terapia Genética
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Células-Tronco Neurais
/
Flucitosina
/
Pulmão
Aspecto:
Preferência do paciente
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2017
Tipo de documento:
Artigo