Genome-Wide Identification and Classification of MicroRNAs Derived from Repetitive Elements
Genomics & Informatics
; : 261-267, 2014.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-113802
Biblioteca responsável:
WPRO
ABSTRACT
MicroRNAs (miRNAs) are known for their role in mRNA silencing via interference pathways. Repetitive elements (REs) share several characteristics with endogenous precursor miRNAs. In this study, 406 previously identified and 1,494 novel RE-derived miRNAs were sorted from the GENCODE v.19 database using the RepeatMasker program. They were divided into six major types, based on their genomic structure. More novel RE-derived miRNAs were confirmed than identified as RE-derived miRNAs. In conclusion, many miRNAs have not yet been identified, most of which are derived from REs.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
RNA Mensageiro
/
Classificação
/
Sequências Repetitivas Dispersas
/
MicroRNAs
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Genomics & Informatics
Ano de publicação:
2014
Tipo de documento:
Artigo