Predictors of Relapse in Patients with Organizing Pneumonia / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 190-195, 2015.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-114250
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients.METHODS:
This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46).RESULTS:
Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively).CONCLUSION:
This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Problema de saúde:
Pneumonía
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Recidiva
/
Capacidade Vital
/
Análise Multivariada
/
Estudos Retrospectivos
/
Seguimentos
/
Pneumonia em Organização Criptogênica
/
Centros de Atenção Terciária
/
Métodos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Tuberculosis and Respiratory Diseases
Ano de publicação:
2015
Tipo de documento:
Artigo