A Case of Subungal Abscess and Onycholysis Induced by Docetaxel / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 125-128, 2007.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-122253
Biblioteca responsável:
WPRO
ABSTRACT
Docetaxel is a taxoid antineoplastic drug, which is widely used to treat locally advanced or metastatic non-small cell lung cancer (NSCLC). Among the adverse dermatological reactions, nail disorders such as bending, onycholysis, hypo- or hyperpigmentation are rare. We report a case of a 62-year-old male with advanced NSCLC (cT4N3M1, stage IV), who developed purulent discharge and onycholysis in the nail of all his fingers and the left great toe after five courses of anti-neoplastic chemotherapy, which included docetaxel (cumulative dose 370 mg/m2, 590 mg). Seven days after the final session of chemotherapy, the patient had become aware of discoloration and swelling of the nail beds with out pain. Three days later, greenish-yellow purulent discharge oozed out from the involved nails. Microbiologic studies revealed Pseudomonas aeruginosa. Intravenous and topical antibiotics (mupirocin) were applied. After 2 weeks, regrown nails were observed and the onycholysis had improved.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pseudomonas aeruginosa
/
Dedos do Pé
/
Hiperpigmentação
/
Carcinoma Pulmonar de Células não Pequenas
/
Abscesso
/
Tratamento Farmacológico
/
Onicólise
/
Dedos
/
Antibacterianos
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Ano de publicação:
2007
Tipo de documento:
Artigo