Association of Immunoglobulin G at Birth with Late-Onset Sepsis and Related Mortality in Very Low Birth Weight Infants
Neonatal Medicine
; : 178-181, 2017.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-122561
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
We aimed to evaluate the association between immunoglobulin G (IgG) at birth and late-onset sepsis (LoS) in preterm infants.METHODS:
Medical records of very-low-birth-weight infants, born at gestational age <28 weeks, between 2013 and 2016, were retrospectively reviewed. Subjects were divided into two groups based on the occurrence of LoS (LoS vs. non-LoS), and IgG levels at 1 day, and at 2 weeks and 4 weeks after birth were investigated. IgG levels, other perinatal factors, and clinical factors were compared in the two groups. The relationship between IgG levels and mortality among infants in the LoS group was also analyzed.RESULTS:
A total of 105 infants were analyzed after exclusion of cases with early onset sepsis or death at < 72 hours of life. Gestational age in the LoS group was lower than in the non-LoS group (25.0±1.8 vs. 26.3±1.4 weeks, P=0.004). IgG levels at birth were similar between the two groups (236.4±96.4 vs. 282.0±104.7 mg/dL, P=0.078). Multivariate analysis showed that IgG at birth was not an independent risk factor for LoS. In the LoS group, IgG levels at birth were comparable between survivors and cases involving mortality.CONCLUSION:
IgG levels at birth were not associated with the occurrence of LoS in extremely preterm infants.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
ODS3 - Meta 3.2 Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
Problema de saúde:
Meta 3.2: Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
/
Sepse
/
Infecções
/
Cuidados de Saúde Neonatal
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Imunoglobulina G
/
Imunoglobulinas
/
Recém-Nascido Prematuro
/
Prontuários Médicos
/
Análise Multivariada
/
Estudos Retrospectivos
/
Fatores de Risco
/
Mortalidade
/
Idade Gestacional
/
Sobreviventes
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Lactente
/
Recém-Nascido
Idioma:
Coreano
Revista:
Neonatal Medicine
Ano de publicação:
2017
Tipo de documento:
Artigo