Modest Improvement of Untreated Severe Sleep-Disordered Breathing in the Middle-Aged and Elderly
Psychiatry Investigation
; : 662-668, 2017.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-123488
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
It has been reported that untreated sleep-disordered breathing (SDB) deteriorates over time, however this remains contentious. The aim of the present study is to evaluate the clinical course of SDB in middle-aged and older SDB patients, and to identify how relevant factors contribute to the change in SDB severity.METHODS:
Baseline and follow-up polysomnographic data of 56 untreated SDB patients (mean age, 61.2±5.71) were obtained retrospectively and the mean interval was 62.4±22.0 months. Subgroup analysis was performed based on the baseline severity, and the factors associated with the course of SDB were analyzed.RESULTS:
At the baseline, 13 subjects were simple snorers, 15 had mild to moderate SDB, and 28 were severe SDB patients. While there was no significant change in apnea-hypopnea index (AHI) as a whole, subgroup analysis showed decrease of AHI in severe SDB patients (43.9±10.6 to 35.6±20.0, p=0.009). The change in supine time percent and baseline AHI were associated with the change in AHI (β=0.387, p=0.003; β=-0.272, p=0.037).CONCLUSION:
Untreated SDB did not deteriorate over time with modest improvement in severe SDB. A proportion of severe SDB patients might expect decrease in SDB severity irrespective of changes in sleep position or body weight.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Síndromes da Apneia do Sono
/
Peso Corporal
/
Estudos Retrospectivos
/
Seguimentos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Psychiatry Investigation
Ano de publicação:
2017
Tipo de documento:
Artigo