Clinical Features and Neurologic Complications of Pediatric Enteroviral Meningitis / 대한소아신경학회지
Journal of the Korean Child Neurology Society
; (4): 246-254, 2017.
Article
em Ko
| WPRIM
| ID: wpr-125194
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To explore clinical features and neurologic complications of pediatric enteroviral meningitis, and to evaluate risk factors according to the presence of cerebrospinal fluid (CSF) pleocytosis and neurologic complications. METHODS: Retrospective review of medical records of patients aged between 1 month and 18 years who were found positive for CSF enterovirus reverse transcription polymerase chain reaction in Dankook University Hospital from March 2009 to February 2015. RESULTS: A total of 151 children was enrolled in the study. Ninety four patients were males and the age at diagnosis was 40.9±47.0 months. Most common season of admission was summer (n=99, 65.6%). Most frequent presenting symptom was fever followed by poor oral intake, decreased activity, and headache. Fifty five (36.4%) patients had no CSF pleocytosis. Complications were observed in 4 (2.6%). Mean blood white blood cell, CSF protein levels were higher, and CSF glucose levels were lower in group with pleocytosis (P < 0.05). There were more seizure development and mental changes, higher peak body temperature, longer fever duration, and longer duration from symptom onset to CSF tapping in group with complications (P < 0.05). All were boys and mean age at admission was younger in group with complications, without statistically significant difference. CONCLUSION: Relatively high proportion of children with enteroviral meningitis showed no pleocytosis. Complications such as meningoencephalitis, refractory status epilepticus, or recurrent seizure rarely occurred, although most had good clinical outcomes.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Estações do Ano
/
Convulsões
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Estado Epiléptico
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Temperatura Corporal
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Líquido Cefalorraquidiano
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Prontuários Médicos
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Reação em Cadeia da Polimerase
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Estudos Retrospectivos
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Fatores de Risco
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Enterovirus
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Observational_studies
/
Risk_factors_studies
Limite:
Child
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Humans
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Male
Idioma:
Ko
Revista:
Journal of the Korean Child Neurology Society
Ano de publicação:
2017
Tipo de documento:
Article