Factor V Gene Polymorphism with Preeclamptic Women in Korea / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
; : 1912-1916, 2002.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-125774
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
This study was to evaluate the association of the G1691A mutation of factor V gene with preeclamptic patients in Korea.METHODS:
Factor V genotype were determined in 113 preeclamptic patients and 100 normotensive pregnant women. A 267 base-pair DNA fragment of the factor V gene that includes nucleotide 1691 was amplified by PCR. PCR product was digested with MnlI restriction enzyme and the fragments were analysed by electrophoresis using 2% agarose gel.RESULTS:
The difference of genetic and allelic frequencies between two groups could not be mentioned because all women were G1691G homozygotes. There was no individuals with mutant allele among preeclamptic patients and control women.CONCLUSION:
There was no evidence of association between preeclampsia and factor V gene polymor- phism in Korean population.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pré-Eclâmpsia
/
Sefarose
/
DNA
/
Fator V
/
Reação em Cadeia da Polimerase
/
Gestantes
/
Eletroforese
/
Alelos
/
Genótipo
/
Homozigoto
Limite:
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2002
Tipo de documento:
Artigo