Inflammatory Myofibroblastic Tumor of the Breast: A Case Report

ABSTRACT

Inflammatory myofibroblastic tumor (IMT) is characterized by a clonal proliferation of myofibroblasic spindle cells, and this is accompanied by a lymphoplasmacytic infiltration. In the majority of cases, this disease has occurred in the lungs and only 9 cases of IMT in the breast have been previously reported. We report here on an IMT in a 25-year-old-female who presented with a palpable mass in the right breast. Histologically, it was characterized by plump spindle cells admixed with prominent inflammation, that was composed of lymphocytes and plasma cells. Immunohistochemically, the spindle cells were positive for vimentin and -smooth muscle actin.