TT Virus (TTV) Infection in General Population, Chronic Liver Diseases, Hemodialysis, and Transfused Patients / 대한임상미생물학회지
Korean Journal of Clinical Microbiology
; : 7-12, 2006.
Article
em Ko
| WPRIM
| ID: wpr-128149
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: TT virus (TTV), isolated initially from a Japanese patient with posttransfusion hepatitis of unknown etiology, was suggested to be a new causative agent of hepatitis. However, it has been found to infect both healthy and diseased individuals and numerous studies have raised questions about its pathogenic role in hepatitis. In order to study its prevalence and clinical impact on hepatitis, we assessed the frequency of TTV DNA. METHODS: Serum samples were obtained from 60 cases of the controls, 77 cases of chronic liver diseases, 44 cases of hemodialyzed patients, and 65 cases of transfused patients. TTV DNA was detected using nested polymerase chain reaction and alanine aminotransferase (ALT), aspartate aminotransferase (AST), and hepatitis B surface antigen (HBsAg) were measured. RESULTS: TTV DNA was detected in 41.7% of the controls, 51.9% of patients with chronic liver diseases, 68.2% of hemodialyzed patients and 61.5% of transfused patients. Comparison between patients with or without TTV revealed no significant differences in AST, ALT, and HBsAg test results. CONCLUSION: The prevalance of TTV infection in patients with chronic liver diseases was similar to that in the controls. TTV infection was not related to abnormal liver function findings and HBsAg positivity. We found no relationship between TTV infection and chronic liver diseases.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Aspartato Aminotransferases
/
DNA
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Reação em Cadeia da Polimerase
/
Prevalência
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Diálise Renal
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Torque teno virus
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Povo Asiático
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Alanina Transaminase
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Hepatite
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Antígenos de Superfície da Hepatite B
Tipo de estudo:
Prevalence_studies
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Clinical Microbiology
Ano de publicação:
2006
Tipo de documento:
Article