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Acute Thrombosis in Coronary and Renal Arteries after Cisplatin and 5-Fluorouracil Administration
Korean Circulation Journal ; : 410-414, 2004.
Article em Ko | WPRIM | ID: wpr-131030
Biblioteca responsável: WPRO
ABSTRACT
A 55-year old male presented with chest and abdominal pain for four hours. One day prior to admission he had received chemotherapeutic agents comprising 130 mg cisplatin and 5,200 mg 5-Fluorouracil for nasopharyngeal carcinoma. EKG showed ST elevations in the leads II, III and aVF. The levels of cardiac enzymes were elevated [creatine kinase (CK) 1129 U/L, CK-MB 180 U/L, troponin T 1.23 ng/mL and troponin I 23.29 ng/mL]. Urokinase was administered at the emergency room, but the patient's chest pain continued with persistent ST segment elevations. Urgent coronary and renal angiograms revealed thrombotic occlusive lesions in the distal right coronary and right renal arteries. Percutaneous transluminal renal angioplasty using 6.0x20 mm balloon was performed for the renal artery. However, filling defects and distal renal flow were not improved and so Abciximab (ReoPro(r)) was administered. Follow-up coronary and renal angiograms on the fifth hospital day showed no filling defects with good distal flow in both right coronary and renal arteries.
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Texto completo: 1 Base de dados: WPRIM Assunto principal: Fosfotransferases / Artéria Renal / Tórax / Trombose / Dor no Peito / Ativador de Plasminogênio Tipo Uroquinase / Dor Abdominal / Seguimentos / Cisplatino / Angioplastia Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans / Male Idioma: Ko Revista: Korean Circulation Journal Ano de publicação: 2004 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Assunto principal: Fosfotransferases / Artéria Renal / Tórax / Trombose / Dor no Peito / Ativador de Plasminogênio Tipo Uroquinase / Dor Abdominal / Seguimentos / Cisplatino / Angioplastia Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans / Male Idioma: Ko Revista: Korean Circulation Journal Ano de publicação: 2004 Tipo de documento: Article