Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences
Natural Product Sciences
; : 71-75, 2015.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-14018
Biblioteca responsável:
WPRO
ABSTRACT
In this study, phytochemical investigation on the aerial parts of Bupleurum falcatum resulted in the isolation of fourteen compounds including three quinic acid derivatives (1 - 3), five flavonoids (4 - 8), three monoterpene glycosides (9 - 11), and three saikosaponins (12 - 14). Compound 1 was first isolated from nature and unambiguously determined to be 3-O-feruloyl 5-O-caffeoylquinic acid on the basis of the extensive spectroscopic evidence. Biological testing revealed that saikosaponin A (12) and saikosaponin D (13) showed moderate antiproliferative effects on HL-60 and HepG2 cancer cell lines.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Quínico
/
Flavonoides
/
Linhagem Celular
/
Bupleurum
/
Glicosídeos
Aspecto:
Pesquisa de implementação
Idioma:
Inglês
Revista:
Natural Product Sciences
Ano de publicação:
2015
Tipo de documento:
Artigo