Age-Related Difference in Long-Term Prognosis of Acute Myocardial Infarction in Women
Korean Circulation Journal
; : 1245-1256, 2000.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-145269
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES:
The purpose of this study was to evaluate the age-related differences in clinical features, coronary anatomy, risk factors, hospital courses, and long-term prognosis of acute myocardial infarction(AMI) in women. MATERIALS ANDMETHODS:
Total 513 female patients with AMI were divided into 3 groups ; group 1(n=3, 50 years old or less), group 2(n=02, between 51 years and 70 years old), and group 3(n=68, older than 70 years). Clinical follow-up including cardiac events was performed for mean duration of 26 months(1~155 months). Cardiac events include cardiac death, reinfarction, CABG, PTCA, CHF, stroke, and recurrent angina.RESULTS:
Minimal lesion(<50% stenosis) in infarct-related artery was more prevalent in group 1 than in group 3(p<0.05). In group 2, the number of low high density lipoprotein(HDL) was significantly more than in group 3(p<0.01). During hospitalization, death and shock were more prevalently observed in group 3 than group 1(p<0.005) and group 2(p<0.001). Group 3 had more heart failures than group 1(p<0.001) and group 2(p<0.001) and group 2 had more heart failures than group 1(p<0.05). The younger age group showed a significantly higher survial rate(7 years group 1; 76.1%, group 2; 60.6%, group 3; 34.2%, p<0.0001, Log Rank Stat =49.4) and cardiac event-free survival rate(7 years group 1; 48.4%, group 2; 32.3%, group 3; 16.0%, p<0.0001, Log Rank Stat =37.5) for each 3 comparisons. In Cox proportional harzard analysis, LV systolic function influenced the group 2 survival (odds ratio 3.8, 95% CI 1.7 to 8.3, p<0.005) and the group 3 survival (odds ratio 2.2, 95% CI 1.1 to 4.5, p<0.05). The cardiac event free survival was influenced by age(odds ratio 1.6, 95% CI 1.2 to 2.1, p<0.005) and LV systolic function(odds ratio 1.8, 95% CI 1.3 to 2.5, p<0.001).CONCLUSION:
Younger female patients with AMI had a more favorable prognosis compared with older female patients. LV systolic fuction was important as a prognostic factor for long-term survival except younger female AMI patients.
Texto completo:
Disponível
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Objetivo 1: Acesso equitativo aos serviços de saúde
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Doença Cardiovascular
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Doença Cerebrovascular
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Doença Isquêmica do Coração
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artérias
/
Prognóstico
/
Choque
/
Fatores de Risco
/
Seguimentos
/
Intervalo Livre de Doença
/
Acidente Vascular Cerebral
/
Morte
/
Coração
/
Hospitalização
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
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Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Circulation Journal
Ano de publicação:
2000
Tipo de documento:
Artigo