Glue Embolization of Aneurysm after Stenting in Canine Carotid Arteries - Technical Feasibility
Journal of the Korean Radiological Society
; : 381-387, 2004.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-149566
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Coiling or infusion of embolic materials into a wide necked aneurysm can be performed with stenting. The purpose of our study is to assess the technical feasibility of aneurysm treatment with glue embolization after stenting. MATERIALS ANDMETHODS:
We used four Wallstents for surgically repairing eight canine carotid aneurysms. After confirmation of the aneurysms on the angiogram, we introduced a 6-7 F guiding catheter in order to deploy the stents. After stenting, we passed a microcatheter into the aneurysm lumen through the stent mesh. 28% glue was slowly injected until the glue cast completely filled the lumen. We evaluated the passage of a microcatheter through the stent meshwork, formation of the glue cast and the stents' ability to protection for any leakage of glue. The follow-up angiogram was obtained for two dogs, one to three times until 8 weeks, and then we sacrificed the dogs and performed pathologic examinations.RESULTS:
Stenting was successful in all cases except one in which the vessel was occluded because the stent was not completely expanded within the lumen. The microcatheter could not pass through the stent mesh in one aneurysm. The two week follow-up angiogram showed complete occlusion of the aneurysm and a patent carotid lumen in a case after successful stenting and glue embolization without distal migration of glue. Tungsten in the glue was noted to migrate out of aneurysm into the soft tissue of the neck. Histopathologic examination showed successful obliteration and stable organization of the aneurysmal lumen with ingrowth of fibroblasts and a foreign body reaction. In contrast, the aneurysms without the glue embolization being performed showed partially thrombosed aneurysmal lumens that became smaller and indistinct on the 8 week follow-up angiograms. Histopathologic examination showed a disorganized thrombus with numerous recanalizations.CONCLUSION:
Glue embolization after stenting could be performed for aneurysm without distal migration of the glue or gluing of the catheter. This concept appears to be useful for applications to the further research and the treatment of aneurysm.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Trombose
/
Tungstênio
/
Artérias Carótidas
/
Stents
/
Aneurisma Intracraniano
/
Adesivos
/
Seguimentos
/
Reação a Corpo Estranho
/
Catéteres
/
Fibroblastos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Animais
Idioma:
Coreano
Revista:
Journal of the Korean Radiological Society
Ano de publicação:
2004
Tipo de documento:
Artigo