Limitations of 99mTc-DMSA scan in diagnosing acute pyelonephritis in children / 소아과
Korean Journal of Pediatrics
; : 408-413, 2010.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-155214
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
We aimed to prove the relative limitation of 99mTc-DMSA scintigraphy (DMSA) compared to computed tomography (CT) in diagnosing acute pyelonephritis (APN) in children.METHODS:
Since September 2006, after a 64-channel CT was imported, 10 DMSA false-negative patients have been identified these patients underwent a CT scan for acute abdomen or acute febrile symptoms and were diagnosed as having APN; however, their DMSA scans were clear. We focused on these 10 DMSA false-negative patients and analyzed their clinical findings and CT results. We used Philips Brilliance Power 64-channel CT scanner for the CT scan and Siemens Orbitor Nuclear Camera 60 Hz for the DMSA scan.RESULTS:
The 10 DMSA false-negative patients were mostly males (80%) and infants (80%). They had fever for a mean of 1.1-day duration before admission and showed increase in acute reactants leukocyte, erythrocyte sedimentation rate, and C-reactive protein. The CT findings of renal lesions were focal in 6 (60%) cases and diffuse in 4 (40%) cases, and most of the lesions were unilateral in 80% of patients. CT proved that 22 renal lesions were neglected by DMSA. Differential renal function test by DMSA was also of no use in the evaluation of renal lesions.CONCLUSION:
In this study, DMSA scan showed limitation in finding renal cortical lesions of CT-proven APN patients. DMSA false-negative results seem to occur at early-phase disease of infantile age, but more prospective studies are needed to determine the reasons and their prevalence.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doenças Negligenciadas
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pielonefrite
/
Sedimentação Sanguínea
/
Proteína C-Reativa
/
Câmaras gama
/
Prevalência
/
Succímero
/
Ácido Dimercaptossuccínico Tecnécio Tc 99m
/
Febre
/
Abdome Agudo
/
Leucócitos
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Criança
/
Humanos
/
Lactente
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2010
Tipo de documento:
Artigo