Exuberant Smooth Muscle Cells in Fibroadenoma of the Breast: A Case Report
Korean Journal of Pathology
; : 431-434, 2010.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-155457
Biblioteca responsável:
WPRO
ABSTRACT
Smooth muscle cell metaplasia is an extremely rare form of stromal differentiation in fibroadenomas. We describe a case of fibroadenoma with exuberant smooth muscle cells in a 72-year-old woman. The mass was located in the upper central portion of the left breast. It was well circumscribed and its greatest dimension was 3 cm. Histologically, the glandular elements resembled the appearance of fibroadenoma, but the stromal elements were composed of spindle cell bundles with abundant eosinophilic cytoplasm and elongated cigar-shaped nuclei. Neither mitotic activity nor cellular atypia was seen. The stromal cells were immunohistochemically positive for smooth muscle actin, calponin, desmin, and estrogen receptor-beta, but negative for CD34, S-100 protein, p63, CD10, estrogen receptor-alpha, progesterone receptor and cytokeratin. These results proved that the stromal cells showed features of smooth muscle cells.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Mama
/
Proteínas de Ligação ao Cálcio
/
Proteínas S100
/
Receptores de Progesterona
/
Actinas
/
Células Estromais
/
Fibroadenoma
/
Citoplasma
/
Células Musculares
/
Miócitos de Músculo Liso
Limite:
Idoso
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pathology
Ano de publicação:
2010
Tipo de documento:
Artigo