The Effect of Cyclosporin Therapy on Endogenous Uveitis

ABSTRACT

Endogenous uveitis is characterized by frequent remissions and exacerbations which lead to visual loss, and treated with immunosuppresive agents. We evaluated the therapeutic effect and complicantions of 15 patients (25 eyes) with endogenous uveitis who were treated with cyclosporin (Implanta). The inflammatory activities of anterior chamber and vitreous were reduced significantly after 1, 3, and 8 month follow-up of cyclosporin therapy, and the visual acuity was improved or sustaind in 52% of all patients. If cyclosporin therapy is intolerable, combining the cyclosporin with low dose of a steroid should be considered.