A Case of Cicatricial Alopecia Associated with Erlotinib
Annals of Dermatology
; : S350-S353, 2011.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-165612
Biblioteca responsável:
WPRO
ABSTRACT
Erlotinib is a small-molecule tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR). Erlotinib has been used primarily to treat non-small cell lung cancer. In addition to its role in tumor cells, EGFR is also an important regulator of growth and differentiation in the skin and hair. Therefore, EGFR-TKIs have been associated with a number of cutaneous side effects including follicular acneiform eruptions, cutaneous xerosis, chronic paronychia, desquamation, seborrheic dermatitis, and hair texture changes. Herein, we report a rare case of a 61-year-old woman who was treated with erlotinib and experienced cicatricial alopecia.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paroniquia
/
Quinazolinas
/
Pele
/
Proteínas Tirosina Quinases
/
Erupções Acneiformes
/
Dermatite Seborreica
/
Carcinoma Pulmonar de Células não Pequenas
/
Alopecia
/
Receptores ErbB
/
Cloridrato de Erlotinib
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2011
Tipo de documento:
Artigo