Topical Autologous Fibronectin in the Treatment of Persistent Corneal Epithelial defects
Journal of the Korean Ophthalmological Society
; : 29-36, 1989.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-167094
Biblioteca responsável:
WPRO
ABSTRACT
Fibronectin, a glycoprotein, is present in plasma and extracellular matrix and is responsible for cellular adhesion. Fibronectin was purified from autologous plasma of two persistent corneal epithelial defect patients by affinity chromatogaphy and administered topically 500 micro ml, 2 dropsper time, five times a day for 3 weeks. Reepithelization began three to seven days after initiation of treatment with autologous purified fibronectin eyedrops, and epithelial defects healed nearly completely and subjective symptoms were relieved. No side effects were observed. Over a follow-up period of 4 to 23 wks, no recurrences were noted.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Soluções Oftálmicas
/
Plasma
/
Recidiva
/
Glicoproteínas
/
Seguimentos
/
Fibronectinas
/
Matriz Extracelular
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
1989
Tipo de documento:
Artigo