The Effect of Carbon Monoxide Intoxication on The Metabolites of Monoamine Neurotransmitters in Human Cerbrospinal Fluid
Journal of the Korean Neurological Association
; : 249-255, 1990.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-168835
Biblioteca responsável:
WPRO
ABSTRACT
This study was done in order to show the effects of carbon rnonoxide (CO) induced hypoxia on the steps of metabolism of rnonoamine neurotransmitters. There were 9 patients exposed to CO and 5 patients of control group. We evaluated their cerebrospinal fluid within 24 hours after CO exposure. And we measured the amounts of 5-hydroxy-indole acetic acid (5-HIAA) and homovanillic acid (HVA) with high performance liquid chromatography (HPLC). In the CO exposure group, the levels of 5-HIAA and HVA were reduced compared with the control group. It was thought that the changes in the levels of 5-HIAA and HVA were due to the transient decrease in monoamine oxidase activity in acute hypoxia.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Carbono
/
Monóxido de Carbono
/
Líquido Cefalorraquidiano
/
Cromatografia Líquida
/
Neurotransmissores
/
Ácido Acético
/
Ácido Homovanílico
/
Ácido Hidroxi-Indolacético
/
Hipóxia
/
Metabolismo
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
1990
Tipo de documento:
Artigo